《催化合成1_3-苯并二恶茂烷的研究》-毕业论文（设计）.doc

PAGE 摘 要 1 ,3-苯并二恶茂烷是一类重要的化合物，其用途也十分广泛，受到生物化学和有机合成等各领域的重视。分子筛由于其独特的催化活性和择形性被广泛用于许多有机合成。 本文研究了H-BEA、H-Y、KSF三种分子筛催化邻苯二酚与苯乙酮合成1 ,3-苯并二恶茂烷反应的活性。研究结果表明，邻苯二酚与苯乙酮合成1 ,3-苯并二恶茂烷反应H-BEA催化剂表现出高于H-Y、KSF催化剂的活性。以转化率、选择性作为指标对反应时间、反应原料摩尔比、催化剂用量等影响因素进行考察，最优条件为原料配比为1：1.4,催化剂用量每摩尔邻苯二酚3.5g，反应时间4 h，在最优条件下的转化率达到34.33 %，选择性为100%。并对产物进行气相色谱—质谱分析鉴定结构和气相色谱分析产物含量。 关键词：苯并二恶茂烷 分子筛 缩合 催化 合成 Abstract 1, 3 - benzodioxoles is a kind of important compound, its application is very wide. It is concerned in the field of biochemistry and organic synthesis. Molecular sieve are widely used in sexual many organic synthesis unique because of shape-selective catalytic activity. In this paper, the catalytic activity of catalyst such as H-BEA, HY, and KSF was investigated to examine the synthesis of 1, 3 – benzodioxoles with catechol and acetophenone. The results show that H-BEA catalyst give superior activity to HY and KSF for the synthesis of 1, 3 - benzodioxoles with catechol and acetophenone. By using conversion and selectivity as indexes, the reaction conditions such as reaction time, the molar ratio of raw materials, the amount of catalyst was examined. The optimal conditions was confirmed that the ratio of catechol to acetophenone=1:1.4, the amount of catalyst= 3.5 g/mole of catechol, reaction time =4h. Under the optimal conditions, the conversion was 34.33%, the selectivity of product was 100%. Furthermore, resultant was identified by gas chromatography - mass spectrometry and the content was analyzed by gas chromatography. Keywords：benzodioxoles molecular sieve condensation catalysis synthesis 目 录 TOC \o 1-3 \h \z \u HYPERLINK \l _Toc232834519 第1章 绪论 PAGEREF _Toc232834519 \h 1 HYPERLINK \l _Toc232834520 1.1 课题背景 PAGEREF _Toc232834520 \h 1 HYPERLINK \l _Toc232834521 1.2 研究目的意义 PAGEREF _Toc232834521 \h 2 HYPERLINK \l _Toc232834522 1.3 国内外研究现状 PAGEREF _Toc232834522 \h 2 HYPERLINK \l _Toc232834523 1.4 主要研究内容 PAGEREF _Toc232834523 \h 3 HYPERLINK \l _Toc232834524 1.4.1 催化剂的制备 P