射干麻黄汤对哮喘大鼠中HIF1α%2cVEGF表达的影响.doc

· ·· Effection of VEGF and HIF-1α in Asthmatic Rats and by Administrated Sheganmahuang Tang Abstract Objectives To evaluate the relationship between VEGF，HIF-1α level and asthmatic chronic rats , to investigate the effect of VEGF and HIF-1α in airway remodeling of chronic asthmatic rats,to reseach the mechanism of Sheganmahuang Tang in asthma treatment. Methods Fifty SD rats were randomly divided into five groups,the asthma chronic model group（group A）, the Sheganmahuang Tang（0.16g）group（group B）, the Sheganmahuang Tang（0.32g）group（group C）, the Sheganmahuang Tang（0.64g） group（group D）,and th