探索殊病人的抗凝策略.pptVIP

与普通肝素或安慰剂相比，磺达肝癸钠降低30天时的死亡＋再梗发生率14％ 磺达肝癸钠的出血风险与普通肝素相比无显著差异 ACS抗凝治疗：STE-ACS非介入治疗—新的证据 EXTRACT TIMI25 中依诺肝素的用量 75 y : 30 mg 负荷剂量 静推  皮下 1.0 mg/kg q12h 2-8天 ≥ 75 y : 无负荷剂量 皮下 0.75 mg/kg q12h 2－8天 CrCl ≤ 30 ml/min: 1.0 mg/kg q24 h * * Although there are a variety of approaches to enhancing anticoagulant effects none are completely satisfactory when used as a single agent. Major categories of anticoagulant therapy include agents that target any one of three main components of the thrombotic process; thrombin, platelets, or fibrin. * As seen in this nomogram each predictor rece