蓝桉的化学成分及其药理活性研究进展-天津中草药杂志社.PDF

中草药 Chinese Traditional and Herbal Drugs 第 46 卷 第 6 期 2015 年 3 月 ·923 · 蓝桉的化学成分及其药理活性研究进展 唐 云，李 伟* 宜春学院化学与生物工程学院，江西省天然活性成分重点实验室，江西 宜春 336000 摘 要：蓝桉 Eucalyptus globulus 是桃金娘科桉属植物，常以叶和果实入药，具有疏风解热、抑菌消炎、防腐止痒等功效。 近年来从其果实、叶和茎皮中发现大量的生物活性成分，如间苯三酚衍生物、黄酮类、三萜类等。现代药理学研究表明，蓝 桉中的化学成分具有抗菌、抗病毒、抗肿瘤、抗氧化和降血糖等多种生物活性。经系统文献调研，对蓝桉的化学成分及药理 作用进行综述，并对蓝桉的开发利用前景进行展望，为进一步合理开发和综合利用蓝桉的药用资源提供参考。 关键词：蓝桉；间苯三酚；黄酮类；三萜；抗菌活性；抗肿瘤 中图分类号：R282.71 文献标志码：A 文章编号：0253 - 2670(2015)06 - 0923 - 09 DOI: 10.7501/j.issn.0253-2670.2015.06.025 Research advances on chemical constituents of Eucalyptus globulus and their pharmacological activities TANG Yun, LI Wei Key Laboratory of Jiangxi Province Natural Active Pharmaceutical Ingredients, College of Chemistry and Biology Engineering, Yichun University, Yichun 336000, China Abstract: Eucalyptus globulus, a kind of plant in Eucalyptus of Myrtaceae family, is commonly used in the leaves and fruits with the function of dispersing wind and clearing heat, bacteriostatic antiphlogistic, and anticorrosion itching. The bioactive chemical constituents in its fruits, leaves, and stem barks are mainly composed of phloroglucinol derivatives, flavonoides, and triterpenoids as well. Many compounds from this plant exhibit the interesting pharmacological activities, such as anti-microbial, antiviral, antitumor, and, anti-oxidant activities, and so on. The recent progress in the studies of the constituents and their pharmacological activity of this plant is reviewed in this paper, by which the prospect of development and utilization of E. globulus could be prospected. It provides the reference for the further development and comprehensive utilization of the resources of E. globulus . Key words: Eucalyptus globulus Labill.; phloroglucinol; flavonoids; triterpenoids; antimicrobial avtivity; antitumor 蓝桉 Eucalyptus globulus Labill. 是桃金娘科 衍生物、黄酮类、三萜类、鞣质酸类以及其他化合物