有机化学双语版+Alcohols,ethers+and+phenols1.ppt

Characteristics of the reaction: Condensation(缩合反应) 2. Only for primary alcohols 3. The temperature of condensation is lower than elimination. 4. SN2 mechanism 1,5-Pentanediol (1,5-戊二醇) Oxane ( 烷)(76%) A. Oxidation of primary alcohols 3-Fluoro-1-propanol (3-氟-1-丙醇) 3-Fluoropropanoic acid (3-氟丙酸) (74%) PCC reagent is soluble in CH2Cl2 P 263 9.3.3 Oxidation of alcohols Secondary alcohols [O] ketones B. Oxidation of secondary alcohols PCC doesn’t attack C=C bond Citronellol (香茅醇) Citronellal (82%) (香茅醛) Chromic acid H2CrO4 C. Oxidation of vicinal diols Vicinal diols react with HIO4, the C-C