丙戊酸钠联合平痫颗粒与卡马西平联合恩必普治疗脑卒中后癫痫的临床疗效、对患者认知功.docVIP

丙戊酸钠联合平痫颗粒与卡马西平联合恩必普治疗脑卒中 后癫痫的临床疗效、对患者认知功能的改善及安全性对比 陈静 目的分析和探讨丙戊酸钠联合平痫颗粒与卡马西平联合恩必 普治疗脑卒屮后癫痫(EAS)的临床疗效、对患者认知功能的改善及安全性。方 法选取我院2013年3月~2014年3月收治的82例脑卒屮后癫痫患者，通过随 机数字表法分为甲组(n=41)和乙组(n=41),甲组患者采用卡马西平联合恩必 普治疗，乙组患者采用丙戊酸钠联合平痫颗粒治疗，对两组患者临床治疗效果、 认知功能改善及不良反应发生情况进行分析。结果甲组患者治疗有效率 75.61%,较乙组87.80%更低(Plt;0.05);甲组患者认知功能改善明显优于乙组 (Plt;0.05)；两组患者不良反应发生率比较无明显差异(Pgt；0.05)o结论针 对脑卒屮沿癫痫患者，丙戊酸钠联合平痫颗粒与卡马西平联合恩必普均能实现不 错的临床效果，前者治疗效果优于后者，后者认知功能改善优于前后，两种方法 治疗不良反应少，安全性高，值得临床推广应用。 关键词 脑卒中后癫痫；丙戊酸钠；平痫颗粒；卡马西平；恩 必普；认知功能；临床疗效 Combined with sodium valproate Pingxian granules and carbamazepine combined grace will be universal in the treatment of post-stroke epilepsy, cognitive function of the patients with improvement and safety compared Abstract Objective to analyze and discuss combined with sodium valproate Pingxian granules and carbamazepine combined grace will be universal in the treatment of post-stroke epilepsy (EAS) the clinical curative effect, on cognitive function in patients with improvement and safety. Methods selected in our hospital in March 2013 2014 March were 82 cases of cerebral stroke in patients with epilepsy after, according to the random number table method were divided into group A (n = 41) and group B (n = 41), Division 1 patients with carbamazepine combined grace will general treatment, group B patients using combined with sodium valproate Pingxian granules treatment, of two groups of patients with clinical curative effect, improve cognitive function and adverse reaction incidence were analyzed. Results group A patients was 75.6%, compared with the group B 87.80% lower (P lt; 0.05); cognitive function in patients with first division improve was significantly better than that of group B (P lt; 0.05). The adverse reactions of the two groups of patients occurred rate had no significant difference (P gt; 0.05). Conclusion for patients with epilepsy after stroke, combined with sodium valproate Pingxian granules and carbamazepine combined Grace amp; P must can achieve good clinical