HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection英文学习资料.pdfVIP

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection g r o s. Ulf Andersson1 and Kevin J. Tracey2 w e . i y v l e n 1Department of Women’s and Children’s Health, Karolinska University Hospital, r o l a e Karolinska Institutet, S-171 76 Stockholm, Sweden; email: Ulf.Andersson@ki.se u s n u n l 2 Feinstein Institute for Medical Research, Manhasset, New York 11030; a. a w n email: kjtracey@ o w s r w e p m r o o r F f . d 1 e 1 d / a 4 o 1 l / n 6 0 w o n D o . n 2 e 6 h 1 Z - n 9 e 3 h 1 S : 9 f 2 o Annu. Rev. Immunol. 2011. 29:139–62 1. n Keywords 1 w 0 o First published online as a Review in Advance on 2. T cytokine, host defense, cell death, ischemia, autoimmunity l y January 4, 2011 o t n i u s r The Annual Review of Immunology is online at Abstract m e v m i I n . U A key question in immunology concerns how sterile injury activates v y This article’s doi: e b innate immunity to mediate damaging inflammation in the absence of R .