心血管治疗药物篇.pptVIP

* This slide shows the comparative effects of the six currently available statins on lipid parameters. All reduce LDL cholesterol and triglycerides, and increase HDL cholesterol. Reference 1. Knopp RH. N Engl J Med 1999;341:498–511. * Epidemiological studies have shown that the incidence of CHD increases with an increase in serum total cholesterol and LDL cholesterol concentrations. These observations led investigators to determine whether cholesterol-lowering therapies, in particular statins, can reduce morbidity and mortality associated with CHD. A number of key studies have been undertake