伴侣动物常见肿瘤疾病.PDFVIP

伴侶動物常見腫瘤疾病 台大動物醫院 王尚麟醫師 Introduction 前言  Neoplasia is the uncontrolled multiplication of abnormal cells 腫瘤就是一群不正常的細胞,不受控制的分裂  Prevalence of cancer in pets is increasing 伴侶動物的腫瘤發生率越來越高 A major cause of pet death 造成死亡的主要原因之一  Early detection and treatment is desirable 早期診斷及治療 Diagnostic method 腫瘤診斷  Fine needle aspiration細針採樣  Impression smears印壓抹片  Scrapings刮削採樣  Pathology病理切片 最準確! Imaging影像診斷  X-ray, CT, MRI  Local invasion局部侵犯  Metastasis遠端轉移 Imaging影像診斷 Paraneoplastic syndromes 腫瘤旁症候群  Neoplasm-associated alterations in bodily structure and function that occur distant to the tumor 腫瘤相關物質造成遠端身體構造及功能之改變  Cachexia惡病質, fever發燒, gastroduodenal ulceration胃十二指腸潰瘍, hypercalcemia高 血鈣, hypoglycemia低血糖, anemia貧血  Can cause greater morbidity than actual tumor 可能造成比原來腫瘤更嚴重的病症 Common type of cancers常見腫瘤 -Lymphoma淋巴瘤  13-24/100000 dogs  FeLV, FIV cats  Lymphadenopathy淋巴結腫大 Cutaneous lymphoma 皮膚型淋巴瘤 Mast cell tumor肥大細胞瘤  16-21% of canine cutaneous tumors  Darier’s sign  Heparin肝素 bleeding出血  Histamine組織胺 edema水腫,ulceration 腸胃道潰瘍 Melanoma黑色素細胞瘤  hairy skin有毛髮的地方 預後較好  Nail bed and mucocutaneous junction 指甲床及皮膚黏膜交界處 預後較差 Mammary gland tumor乳房腫瘤  Dog ◦ 260/100000 intact bitch未結紮母犬 ◦ 50% benigh,50% malignant 良惡性約各占一半 ◦ Caudal mammary glandscranial 後側乳房發生率較高 ◦ OHE when young reduce the risk早期結紮可降低發生率  Cat ◦ Third most frequent tumor 第三常見腫瘤 ◦ 80% are malignant 惡性機率高 Lipoma脂肪瘤  Rubbery consistency 橡膠樣觸感  Slow growing生長速度緩慢  Older obese dog老年肥胖狗常見 Nasal tumor鼻腔腫瘤  Epistaxis鼻出血, mucopurulent discharge 黏液濃樣分泌物, dyspnea呼吸困難, facial deformity臉部變形 Osteosarcoma骨瘤  85% of malignancies originating in