基于喹啉和罗丹明为母体的荧光化学传感器的设计、合成以及性能研究-有机化学专业论文.docxVIP

优秀毕业论文 精品参考文献资料 AbstractAb Abstract Ab stract Now,more and more research proves that the amino acids in the body not only as the substrate material of synthetic protein，they can by themselves and their metabolites have the biological activity of regulating role on animal body in many life activities，such as regulating metabo lism of nutrients(protein metabolism and lipid metabolism，glucose metabolism，etc．)，maintain the body’S homeostasis，affecting the nervous and endocrine，control the basic expression and signal transduction，immune cells，the function such anti-oxidation，anti-stress，these regulation Can eventually affect the organism’S development and health．And these are dependent the concentration of amino acids in normal range，concentration above and below normal will become a cause of the disease．A typical example：a higher than normal amount of Cys(1 9 umol／1)，can lead to coronary heart disease，stroke，atherosclerosis， and SO on．Therefore，development of amino acid of qualitative and quantitative analysis for detecting technology has very important scientific value and research significance． Fluorescent chemical sensor is different from traditional testing organism biological small moleculescontent detection tools，its high sensitivity，high selectivity， easy synthesis，cheap and good biological characteristics，make its have gradually become the main testing tool in life science and environmental science．It’S more effective to help US to observe and understand the activites from microviews through that researching the reaction between fluorescent chemosensors and bioactive substances．It has been hot studying subject that design and synthesis sensitive and selective organic small．molecule fluorescent chemosensorS in bioscience and environmental fields．However，the most of traditional fluorescent chemosensors are one．photon(OP)fluorescent chemosensors．They possess some disadvantages like photobleaching，interference from autofluorescence in cells and tissues，shallow pen