心肌梗死加重冠状动脉粥样硬化的进程好microsoftword文档.docVIP

急性心肌梗死加重动脉粥样硬化 6月27,Nature杂志在线报道了心肌梗塞加重动脉粥样硬化机制的最新进展。探求斑块中过剩的单核细胞的来源，研究者发现， HYPERLINK /Search.asp?Field=TitleClassID=keyword=心肌梗死 心肌梗死通过交感神经系统的信号将造血干细胞和祖细胞从骨髓微环境中动员出来。这些造血祖细胞，随后接种到脾，产生持续增加的单核细胞生成(如下图)。这些观察到的现象为理解动脉粥样硬化的发生机制提供了新的线索，并为减轻病情进展，提供了一种新的治疗机会。 Myocardial infarction accelerates atherosclerosis 梗塞加重冠状动脉粥样硬化的机制 学者们推断再梗塞反映了疾病进展的后期阶段。最近一项研究验证了这一假说：心肌梗塞激发的炎症旨在修复损失的心脏，却加剧了动脉粥样硬化的形成，即心肌梗塞促发动脉粥样硬化 ADDIN EN.CITE EndNoteCiteAuthorDutta/AuthorRecNum102/RecNumrecordrec-number102/rec-numberref-type name=Journal Article17/ref-typecontributorsauthorsauthorDutta, Partha/authorauthorCourties, Gabriel/authorauthorWei, Ying/authorauthorLeuschner, Florian/authorauthorGorbatov, Rostic/authorauthorRobbins, Clinton S./authorauthorIwamoto, Yoshiko/authorauthorThompson, Brian/authorauthorCarlson, Alicia L./authorauthorHeidt, Timo/authorauthorMajmudar, Maulik D./authorauthorLasitschka, Felix/authorauthorEtzrodt, Martin/authorauthorWaterman, Peter/authorauthorWaring, Michael T./authorauthorChicoine, Adam T./authorauthorvan der Laan, Anja M./authorauthorNiessen, Hans W. M./authorauthorPiek, Jan J./authorauthorRubin, Barry B./authorauthorButany, Jagdish/authorauthorStone, James R./authorauthorKatus, Hugo A./authorauthorMurphy, Sabina A./authorauthorMorrow, David A./authorauthorSabatine, Marc S./authorauthorVinegoni, Claudio/authorauthorMoskowitz, Michael A./authorauthorPittet, Mikael J./authorauthorLibby, Peter/authorauthorLin, Charles P./authorauthorSwirski, Filip K./authorauthorWeissleder, Ralph/authorauthorNahrendorf, Matthias/author/authors/contributorstitlestitleMyocardial infarction accelerates atherosclerosis/titlesecondary-titleNature/secondary-title/titlesperiodicalfull-titleNature/full-title/periodicalvolumeadvance online publication/volumedates/datespublisherNature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved./publisherurlsrelated-urlsurl/10.1038/nature11260/urlurl/nature/journal/vaop/ncurrent/abs/nature11260.html#supplementary-information