基于量子点及其复合物的光电免疫分析新方法-有机化学专业论文.docxVIP

优秀毕业论文 精品参考文献资料 基于量子点及其复合物的光电免疫分析新方法Hi 基于量子点及其复合物的光电免疫分析新方法 Hi曲ly Sensitive Photoelectrochemical Immunosensors based on Quantum Dots and their Nanocomposites Abstract Photoelectrochemical(PEC)immunoassay iS a newly eme略ed detection method．which possesses the advantages of high sensitivity，good selectivity，easily minimized instrument， and great potential for infield analysis．Due to these merits，it has attracted considerable attentions in th analytical chemistry field．During the past two decades，a variety of novel PEC immunoassay methods have been developed and showed great potential in the fields of clinical diagnosis．environmental monitor,and food safety．However,in comparison to th。eir electrochemical and photochemical counterparts．the study of PEC immunoassay iS stillin the eaily stage．Nowadays，only a few kinds of PEC active nanomaterials could be applied for PEC immunoassay，the detection model which could effectively improve the analytical performance of the immunosensor iS limited．and the sensitivity of the PEC immunoassay method still has big room to be improved．To solve these problems，this thesis developed two novel PEC immuassay methods，based on a newly synthesized graphene and CdTe(GR-CdTe) nanocomposite and a novel exciton-exciton interaction mechanism．UIlder optimal conditions， both PEC immunosensors showed high sensitivity，good stability，and acceptable accuracy for the detection of carc洫oembryoIlic antigen(CEA)，an important tumor marker involved in many malignant cancers．The detailed information iS as follows： 1．One-pot synthesis of G10CdTe nanocomposites and their application for highly sensitive PEC immunoassay． A one．pot synthesis procedure was developed for the preparation of GR-CdTe nanocomposites，which was simple，fast，and could lead to the formation of a high quality GR．CdTe nanocomposite谢m good water dispersibility，excellent conductivity，high CdTe quantum dots(QDs)loading density and good PEC activity．111e synthesis mechanism was investigated by a