基于血清胃蛋白酶原水平胃癌前病变不同证候类型的癌变风险研究-中医内科学专业论文.docxVIP

优秀毕业论文 精品参考文献资料 研究生优秀毕业论文 2．血清 2．血清PG检测结果：阴性26例，占总数19．55％；轻度阳性53例，占总数39．85％； 中度阳性36例，占总数27．07％；强阳性18例，占总数13．53％。 3．各种证型与血清PG检测结果之间的相关性：阴性患者常见于胃阴不足证、 肝胃气滞／气阴两虚证、湿热蕴胃／胃阴不足证，轻度阳性患者常见于脾胃虚寒证、湿 热蕴胃证、肝胃气滞证，中度阳性一强阳性患者常见于瘀阻胃络／气阴两虚证、湿热蕴 胃／脾胃虚寒证；瘀阻胃络／气阴两虚证、湿热蕴胃／脾胃虚寒证血清PGI水平、PGR 值下降显著。 结论： 1．PLGC中医证候类型以虚实关联证居多，证候结构具有多态性与动态性的特征； 2．血清PG中度阳性一强阳性常见于瘀阻胃络／气阴两虚证、湿热蕴胃／脾胃虚寒证； 3．PLGC具有癌变高危风险的证候类型可能为湿热蕴胃／脾胃虚寒证、瘀阻胃络／ 气阴两虚证。 关键词： 慢性萎缩性胃炎癌前病变；血清胃蛋白酶原；中医证候；癌变风险 Study Study On Re I at i onsh i P Between TCM Of Precancerous Les i on Of Oh ron i c Atroph i c gastr i t i S (PLGC)W i th PG I、PG I I And PGR SpeciaIty： InternaI mediCi Re of TOM Author： J i an Song Tutor： Youzhang LiU Abstract ObjectiMe Precancerous lesion of chronic atrophic gastritiS(PLGC)iS one of the most common and multi-occurred diseases in the digestive system which iS hard to be cured，and there iS cancerous trend especially those with intestinal metaplasia／atypical hyperplasia，SO it iS increasingly getting the social attention． Active prevention， early diagnosiS and treatment are of significance for preventing gastric cancer． The purpose of thiS research iS to study the correlation between different TCM syndrome types and positive serologic test results of chronic atrophic gastritis precancerous according to the examination of serum pepsinogen(PG) as a result，then to identify the TCM syndromes with highest risk of cancer， SO as to provide an early warning for the cl inical treatment． Contents and Methods Based on TCM basic theory and related medical literature research， diagnostic data of 133 PLGC patients diagnosed through electronic gastro scope and gastric mucosa pathological biopsy were collected through clinical expert consultation method，TCM dialectical thinking and epidemiological cross—sectional survey research methods．TCM syndrome types were identified through“The Nakedness of Chronic Atrophic Gastritis to Cancer Associated Card Syndrome Differentiation System”．The serum pepsinogen(PG)results whi