健侧重复经颅磁刺激对脑外伤患者记忆和生活质量的影响.PDFVIP

中国康复理论与实践2017年10月第23卷第10期ChinJRehabilTheoryPract,Oct.,2017,Vol.23,No.10 - 1180 - DOI: 10.3969/j.issn. 1006-9771.2017.10.012 ·临床研究 · 健侧重复经颅磁刺激对脑外伤患者记忆和生活质量的影响① 王单，麦荣康，王敏，谭婷婷，朱芬，陈尚杰，黄居科 [摘要] 目的 观察健侧低频重复经颅磁刺激(rTMS)对脑外伤患者的记忆和生活质量的影响。方法 2013 年9 月至2015 年6 月，本院60 例脑外伤后记忆功能障碍患者，随机分为对照组(n=30)和观察组(n=30) 。两组均给予常规神经外科治疗。观察组在此 基础上予以健侧低频rTMS 治疗，每天治疗1次，每周连续治疗5 d ，休息2 d ，共治疗4 周。观察两组患者治疗前后Rivermead 行为 记忆测验(RBMT)和世界卫生组织生活质量测定简表(WHOQOL-BREF)评分的差异。结果 治疗后，对照组RBMT 评分较治疗前无 显著性差异(t= 1.233, P=0.223) ，观察组RBMT 评分较治疗前提高(t=2.186, P=0.033) ，两组RBMT 评分无显著性差异(t= 1.133, P= 0.262) 。治疗后，对照组WHOQOL-BREF 评分仅在生理领域较治疗前显著提高(t=5.606, P0.001) ，观察组WHOQOL-BREF 评分在 生理领域、心理领域、环境领域均较治疗前明显提高(t2.879, P0.01) ；观察组WHOQOL-BREF 评分在生理领域、心理领域和环 境领域均高于对照组(t2.095, P0.05) ，两组社会领域评分之间无显著性差异(t=0.508, P=0.614) 。结论 健侧低频rTMS 可能对脑外 伤患者记忆功能和生活质量的改善有促进作用。 [关键词] 脑外伤；重复经颅磁刺激；记忆；生活质量 Effect of Low Frequency Repetitive Transcranial Magnetic Stimulation at Uninjured Side on Memory and Quali- ty of Life in Patients with Traumatic Brain Injury WANG Dan, MAI Rong-kang, WANG Min, TAN Ting-ting, ZHU Fen, CHEN Shang-jie, HUANG Ju-ke Department of Rehabilitation, the Affiliated Shenzhen Baoan Hospital of Southern Medical University, Shenzhen, Guangdong 518101, China Correspondence to HUANG Ju-ke . E-mail: bayyhjk@163.com Abstract: Objective To observe the effect of low frequency repetitive transcranial magnetic stimulation at uninjured side on memory and quality of life in patients with traumatic brain injury. Methods From September, 2013 to June, 2015, 60 cases of memory impairment af- ter traumatic brain injury were randomly divided into control group (n=30) and observation group (n=30). The control group was given neu- rosurgical conventional treatment; the observation group was given low frequency repetitive transcranial magnetic stimulati