右美托咪啶在病态肥胖患者腹腔镜手术中的药代动力学和药效学.PDFVIP

右美托咪啶在病态肥胖患者腹腔镜手术中的药代动力学和药效学 Pharmacokinetic and pharmacodynamics of intravenous dexmedetomidine in morbidly obese patients undergoing laparoscopic surgery. 摘要翻译 田 磊 原文摘要 BACKGROUND: This study was designed to investigate the pharmacokinetics and pharmacodynamics of dexmedetomidine in morbidly obese patients undergoing laparoscopic surgery. METHODS: Morbidly obese (body mass index ≥40 kg/m2) and normal weight patients scheduled for elective laparoscopic surgery were included (n = 8, each group). After baseline hemodynamic