静电纺丝制备聚电解质基核-壳结构纳米纤维与其应用.pdfVIP

ABSTRACT Electrostatic spinning is a direct and relatively easy method for making nanometer fiber. Core-shell structure nanofiber is a common one of the composite nanofibers, which is generally composed of two or more polymers prepared by the electrospinning. The inner and outer portions of fiber is constituted by different substances, the nanaofibers show a double or even more different layer structure, different compositions result in the inner and outer layers of nanofibers have different functions. A variety of nanofibers can be prepared by changing the diameter and components of nanofibers. Natural polymers have rich resources 、species diversity, renewable, excellent biocompatibility, biodegradability performance. Nonwovens based on electrostatic-spun natural polymer fibers have many potential applications in medical field such as wound dressing, tissue engineering scaffold and drug delivery system. In this paper, core-shell structure polyelectrolyte nanofibers has been prepared by the electric field induced phase separation, and microstructure 、properties and applications of the nanofibers are studied and characterized. The main content are as follow: 1. Core-shell structured PEO-chitosan nanofibers have been produced from electric field inducing phase separation. Chiotsan, a positive charged polymer, was dissolved in 50 wt % aqueous acetic acid and the amino group on polycation would protonize, which would endow chitosan electrical properties. Chitosan molecules would move along the direction of the electric field under the electrostatic force and formed the shell layer of nanofibers. Preparation process of core-shell structure is quite simple and effici