骨质疏松症需要长期治疗以达到最终降低骨折风险的疗效.pptVIP

Yood * * Slide 33: Probability of Fracture Over 24 Months for BisPhosPhonate-treated Subjects Using the range of MPR values from 0 to 1.0, Siris et al calculated the Probability of a fracture as a function of MPR. As seen on this slide, the Probability of fracture is essentially unchanged for MPRs of 50% or less. The Probability declines modestly at MPRs between 50% and 74% and are sharPly decreased for Patients with MPRs of 75% or more. For a Patient on a weekly bisPhosPhonate regimen, 50% comPliance is equivalent to missing one dose out of every two weeks. According to this model, such a