母猪初情期全基因组关联分析和位置候选基因研究.pdfVIP

ABSTRACT ofPCR from6 boars．ThesethreeSNPswere throughdirectlysequencingproductsFI in and fromthewhite F0，Fl 454 F2 genotyped phenotyredgilts resource SNaPShot associationofLIN28Bexonl populationby method．Significantly TMEM38Bexonl GAwithat were GAand A正Exon2 agepuberty g．771 g．243 g．488 association this associationwasnot standard analysis．Butsignificant detected(P0．05)in L1N28Band detectedinthemarker-assistedassociationtestand that F-droptest，indicating TMEM38Bwerethe linkedwitll trait for at on genesclosely quantitativegeneagepuberty SSC1．Theresultsconfkrmedthe results，andimportant previousQTLmapping provide duesforfurtherisolationof traitmutationsand for at agepuberty． quantitative genes at association words：agepuberty，genome—widestudy，candidategenes，F2 Key resource of family． generation IV 5数量性状位点(QTL)精细定位策略……………． 5．1候选基因分析． 5．2连锁和连锁不平衡分析(LDLA) ．7 53同源相同精细定位分析(IBD) ．8 6母猪初情期候选基因LIN28B和TMEM38B的研究概况 ．8 6．1LIN28B基因的研究进展 6．2TMEM38B基因的研究进展 lO 7本研究的目的和意义