聚焦超声治疗583例外阴上皮内非瘤样病变的临床疗效分析.PDF

Med J Chin PLA, Vol. 40, No. 6, June 1, 2015 　463 论　著 聚焦超声治疗583例外阴上皮内非瘤样病变的临床疗效分析 裴娇娇，常淑芳，孙江川，张潇元，丹阳，唐远红 [摘要]　目的　观察聚焦超声治疗外阴上皮内非瘤样病变的近远期疗效，并分析影响疗效的相关因素。方法　收 集2004年1月－2014年6月在重庆医科大学附属第二医院接受聚焦超声治疗的外阴上皮内非瘤样病变且具有完整随访资 料的患者583例，回顾性分析其疗效、并发症及其相关影响因素。结果　聚焦超声治疗外阴上皮内非瘤样病变总有效 率为97.43% ，复发率28.65% ，并发症发生率9.09% 。其疗效与患者是否接受再次巩固治疗有关，接受巩固治疗的患者其 有效率明显上升(P 0.05) ；并发症的发生与治疗方式有关，使用CZF300机型高功率短时间治疗者并发症发生率明显高 于使用CZF-1机型低功率长时间治疗者(P 0.001) 。结论　聚焦超声治疗外阴上皮内非瘤样病变疗效可靠，采用多次巩 固治疗及低功率长时间治疗方案可提高疗效，降低并发症发生率。 [关键词]　超声，高强聚焦；外阴疾病；治疗结果 [中图分类号]　R711.72　　　　[文献标志码]　A　　　　[文章编号]　0577-7402(2015)06-0463-04 [DOI]　10.11855/j.issn.0577-7402.2015.06.08 Clinical effect of focused ultrasound on the treatment of nonneoplastic epithelial disorders of vulva: a retrospective study of 583 cases PEI Jiao-jiao, CHANG Shu-fang, SUN Jiang-chuan, ZHANG Xiao-yuan, DAN Yang, TANG Yuan-hong Department of Obstetrics and Gynecology, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China This work was supported by the National Natural Science Foundation [Abstract]　Objective　To evaluate the short and long-term effect and explore the potential influential factors of focused ultrasound in the treatment of nonneoplastic epithelial disorders of vulva (NNEDV). Methods　Clinical data of 583 patients suffering from NNEDV which was treated with focused ultrasound admitted from Jan. 2004 to Jun. 2014 to the hospital the authors served were collected. The treatment effects, complication rate, and potential influential factors were retrospectively analyzed. Results　The total effective rate of focused ultrasound in treating NNEDV was 97.43%, the recurrence rate was 28.65%, and the complication rate was 9.09%. The effective rate was significantly increased after a course of strengthened treatment (P 0.05). The incidence of complications of CZF