血液灌流联合血液透析对尿毒症钙磷代谢及皮肤瘙痒的影响.PDFVIP

《中国医学创新》第 12 卷 第 5 期（总第 323 期）2015 年 2月　　论　　著 Lunzhu 血液灌流联合血液透析对尿毒症钙磷代谢 及皮肤瘙痒的影响 ① ① ① 冯敏坚 　刘新 　王文凤 【摘要】　目的： 方法： 　　 探讨血液灌流联合血液透析对尿毒症患者钙磷代谢及皮肤瘙痒症状的影响。 选择 42 例尿毒症患者为研究对象。将 42 例患者按照随机数字表法分为观察组和对照组。观察组 18 例，接受血液透 析联合血液灌流治疗；对照组 24 例，接受单纯血液透析治疗。比较两组治疗前后钙、磷、皮肤瘙痒情况及生 活质量。结果：治疗 4、8 周后观察组钙磷乘积明显较治疗前改善（P0.01），且较同期对照组改善明显，差异 有统计学意义（P0.01）；治疗 4、8 周后观察组血清磷水平明显较治疗前改善（P0.01），且较同期对照组改 善明显，差异有统计学意义（P0.01）。治疗后 4、8 周观察组皮肤瘙痒情况明显较治疗前好转，且较同期对照 组患者皮肤瘙痒情况改善明显，差异有统计学意义（P0.001）；治疗后观察组生活质量明显高于对照组，差异 有统计学意义（P0.001）。结论：血液灌流联合血液透析可有效纠正尿毒症患者血钙磷代谢紊乱，明显减轻患 者皮肤瘙痒症状。 【关键词】 　　 　尿毒症；　血液灌流；　血液透析；　疗效 　　Influence of Blood Perfusion Combined with Hemodialysis on Calcium and Phosphorus Metabolism and Skin Pruritus Symptoms of Patients with Uremia/FENG Min-jian，LIU Xin，WANG Wen-feng.//Medical Innovation of China，2015，12（05）：001-004 　　【Abstract】　Objective：To study influence of blood perfusion combined with hemodialysis on calcium and phosphorus metabolism and skin pruritus symptoms of patients with uremia. Method：42 uremia patients were selected as the research object.According to random number table method 42 patients were randomly divided into observation group and control group. Observation group： 18 patients， treated with hemodialysis combing blood perfusion；Control group：24 cases， pure hemodialysis therapy. Calcium， phosphorus， skin pruritus conditions and quality of life of two groups before and after the treatment were compared. Result：4 weeks， 8 weeks after treatment，serum calcium level of observation group was obviously improved than before the treatment（P0.01），and the control group improved significantly during this period， and there were statistically significant difference（P0.01）；4 weeks，8 weeks after treatment，serum phosphorus