B型钠尿肽及N端B型钠尿肽原水平与心力衰竭患者心功能的关系.PDFVIP

·58· 文章编号：1001_2087(2006)01一0058旬3中图分类号：R446．1 文献标识码：A B型钠尿肽及N端B型钠尿肽原水平与 心力衰竭患者心功能的关系 童华诚1， 郭玉军2， 李玲1， 苗晓亮1 (1．威海金海湾医院检验科，山东威海264209；2．威海金海湾医院心内科，山东威海264209) BNP)水平与HF患者 摘要：目的研究心力衰竭(HF)患者B型钠尿肽(BNP)、N端B型钠尿肽原(NT—pr0 30例有呼吸困难的非HE患者(对照组)BNP、NT-proBNP水平并以多普勒超声诊断仪测定左室射血分数 (LVEF)。结果 诊断。 关键词：B一型钠尿肽；N端B型钠尿肽原；心力衰竭 The betweennatriureⅡc ternliIIal natriureticleVelsand relationsIlipB-type pepHde，N pro·B-type peptide inheartfailure cardiacfunction pati蛐ts册，vG月∞ck昭，G册脚m，Ⅱ厶愕，^删O尉∞眈增．脚8疗胱眦矿 ain把Ⅱf如60mfo可，耽i^谢GD地nB0y舶印i把z，鼽Ⅱ，础昭耽i^反264209，吼i耽 To thecorrelationbetweenlevelsof natmretic te瑚i- Abst阳ct：objectiveinvestigate B—t)『pe peptide(BNP)，N nal natriuretic NewYorkheart in with association(NYHA)classification pro—B—type peptide(NT—proBNP)and patients hean ThelevelsBNPin86 withHFaIld30non—HF with of failure(HF)．Methods patients patientsdyspnea(the measured and 1evelsmeasured leftventricularfraction controls)were IRMA， byEUSA， ejection by NT—pmBNP detemined ResultsBNPand levelsincreasedwithincrement (LVEF)was bydopplerechocardio静．aphy． NT—pmBNP of toincrementof NYHAclassificationand con．elatedwith severityaccor击ng degree negatively LVEF，r=一0．39，P 0．01and levelofBNP coITelatedwith r=一0．35，P0．01I℃spectively．The significanny NT—pmBNP(r=0．91，P and inHF ef玷ctwereevaluatedwithreceiver 0．001)．BNP