冠状动脉病变及介入治疗对QT离散度的影响.docxVIP

冠状动脉病变及介入治疗对QT离散度的影响 DOI： 10.7504/nk2016010203 中图分类号：R587.1 文献标识码：A 摘要：目的探讨QT离散度(QTD)与冠状动脉病变的关系以及冠状动脉介入 治疗对QT离散度的影响。方法 对2230例行选择性冠状动脉造影和(或)冠状 动脉支架植入术患者的冠状动脉造影结果及心电图QTd及QTcd进行分析。结果 正常组与轻度狭窄组之间无明显差异(Pgt；O?05)；正常组与中重度狭窄组之间 有明显差异(p0.05)；中度狭窄组与重度狭窄组之间有显著差异(p0.01)o 单支病变与正常组比较差异显著(Plt;0?01)；多支病变组与双支病变组比较、 双支病变组与单支病变组比较，差异均显著增大(Plt;O?05)。结论QTd增大提 示冠脉狭窄更严重、病变范围更广泛，冠状动脉病变严重者行支架植入术后QTd 明显减短。QTd能成为临床上预测冠脉病变及支架植入术疗效的一项无创性指标。 关键词：冠状动脉狭窄；冠状动脉造影；冠状动脉介入治疗；QT离散度 Abstract:Objective To discuss the relati on ship between QT dispersi on degree (QTD) and cor on ary artery lesio ns and the effects of Cor on ary artery in terventio n treatme nt on QT dispersion degree. [Methods]A nalysisi ng the Cor on ary an giography results and Electrocardiogram QTd and QTcd of 2230 patients who had been Carried out Cor on ary an giography or (and ) Cor on ary artery stent impla ntati on. Results There was no difference between normal group and mild stenosis group (P gt; o. 05).There was obvious d iff ere nee betwee n n ormal group with moderately severe stenosis group (p lt; 0.05).Between the moderate stenosis group and severe stenosis group there were significant differences (p lt; 0.01).Single lesion significant difference compared with the normal group (P lt; 0.01).Multivessel lesions and pathological changes of double branch group were significant differenee (P lt; 0.05).Double branch lesions and single lesion group were significant differenee (P lt; 0.05) too. Conclusions The greater the QTd whose Coronary artery stenosis is serious and lesion is more extensive.After stent implantation Q.Td would significantly shorte n.QTd can become a non?in vasive in dicatorTo predict cor on ary lesi ons and the effect of stent implantation. Key words: Coron ary artery stenosis ; Cor on ary angiography; Cor on ary artery intervention treatment; QT dispersion degree. QT离散度(QT intervention dispersion QTD)是指体表十二导联心电图的各 导联中最大QT间期(QTcmax)与最小QT间期(QTcmin)的差值，它代表阶段 性心肌复极差异，反映各部分心肌复极不均，极易发生室性折返激动，代表了心 室肌电的不稳定，是一项预测心脏复极同步