兔视神经间接损伤的视神经组织压观察.docxVIP

兔视神经间接损伤的视神经组织压观察 The optic nerve tissue of the rabbits optic nerve is obserated Update date: 2011-06-16 jiang lai ma zhi-hai Yang bingjian 【abstract 】 objective to indirect optic nerve injury by observing the rabbit optic nerve tissue after the change of the pressure, the secondary injury after indirect optic nerve injury mechanism are discussed. Method a side 24 h after optic nerve injury, micro puncture method is used to record the damage side and contralateral ball after 2 mm of the optic nerve tissue pressure change, and take the pressure after the start of 40 ~ 60 min is analyzed by the average pressure value? 24 h after the results of indirect optic nerve injury, the injury side nervous tissue pressure (0. 315 + 0. 334) kPa (1 kPa 二 7. 5 mm Hg) was significantly higher than that of the contralateral kPa (0.085 + 0.085) (P 0.01). Conclusion it is necessary to implement the optic nerve decompression technique? [keywords] the optic nerve: Trauma and injury: Pressure, organization Observation of optic nerve tissue pressure of indirect optic nerve injuries in rabbits JIANG li, MA Zhizhong, TAO Hai, et al. Dept. Of Ophthalmology, 301st Hospital of the PLA, Beijing 100583, China [Abstract] Objective To determine the role of optic nerve swelling in secondary damage of optic nerve by measuring the tissue pressure of intraorbital optic nerve of injured and nOTinally-controlled eyes of rabbits? Methods Micropipette connected with a pressure transducer was placed in a micromanipulator. Twenty-four hours after injury,the pipette was inserted into intraorbital optic nerve tissue approximately 2mm behind the globe to measure the tissue pressure, and the average pressure from 40 to 60 min after recording was compared and analyzed? Results Twenty-four hours after injury,the pressure of the injured optic nerve tissue (0. 315±0. 334 kPa, n二 12) was significantly higher than that of the normal control ( —0. 085±0. 213 kPa, n=12； P0. 01). Conclusions When the injured optic nerv