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29.03%, 19.53% and 24.19% respectively, these antibodies were higher than those of controls (P0.01). Using multiple logistic regression analysis , thyroperoxidase antibodies positive rate was still statistically significant (P=0.002,OR =5.000).
The differences were no significance if they had one of causes which include chromosome abnormality, uterus abnormal, chlamydia and mycoplasma infection, TORCH infection, endocrine abnormality, anticardiolipin antibody and other autoimmune antibodies positive expression.
In case group, whether two pregnancy losses、three or more consecutive
pregnancy losses; primary RSA and secondary RSA; ealy RSA and late RSA; the positive rates of tithyroid autoantibodies, hyroperoxidase antibodies and hyroperoxidase antibodies were no statistically significance.
In case group, whether tithyroid autoantibodies were positive or not, the positive rates of anticardiolipin antibody, antisemen antibody and endometrium antibody were not statistically significant.
The age was accordance whether the tithyroid autoantibodies were positive or not.
The differences were not statistically significant.
Conclusion:
There is a significant correlation between tithyroid autoantibodies and RSA, the positive rates of tithyroid autoantibodies, thyroglobulin antibodies and thyroperoxidase antibodies are higher significantly, quantitate level of thyroperoxidase antibodies is higher, and tithyroid autoantibody positive is a independent risk factor.
There are no relationship between tithyroid autoantibody and the other factors such as abnormal thyroid function, maternal age, abortion number, the period of abortion, whether normal labor in RSA or not and so on . There are also no relationship between antithyroid antibody, anticardiolipin antibody, antisemen antibody and endometrium antibody.
Keywords: thyroglobulin antibody; thyroperoxidase antibody; spontaneous abortion;
recurrent
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中英文缩略词表
英文缩写 英文全称 中文对照
TA t i t hyr oi d aut oant i body 甲状腺自身抗体 RSA r ecurr e
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