纳米金在肿瘤检测及放射治疗中的应用-中国光学-上海应用物理研究所.PDF

第34 卷 第4 期 辐射研究与辐射工艺学报 J. Radiat. Res. Radiat. Process. Vol.34, No.4 2016 年8 月 /fushe/CN/volumn/home.shtml August 2016 纳米金在肿瘤检测及放射治疗中的应用 1 2 1 1 1 1 1 韦贵生 相法伟 田 甜 林承列 李 茜 李 江 王丽华 1 （中国科学院上海应用物理研究所 物理生物学研究室与上海同步辐射光源生物成像中心 嘉定园区 上海 201800 ） 2 （山东省潍坊市人民医院放射科 潍坊 261000) 摘要 简述纳米金探针的组装和检测原理，总结了纳米金探针在肿瘤细胞检测、医学成像和放射治疗中的应 用进展，并对其在今后的应用发展前景进行了展望。 关键词 纳米金，生物探针，肿瘤检测，放射治疗 中图分类号 TL13 ，Q6-33 ，R815 DOI: 10.11889/j.1000-3436.2016.rrj.34.040103 Application of gold nanoparticles in tumor detection and radiation therapy 1 2 1 1 1 1 1 WEI Guisheng XIANG Fawei TIAN Tian LIN Chenglie LI Qian LI Jiang WANG Lihua 1(Division of Physical Biology Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Jiading Campus, Shanghai 201800, China) 2(Department of Radiology, People’s Hospital of Weifang, Weifang 261000, China) ABSTRACT Preparation and working principle of molecular probes based on gold nanoparticles were introduced, and recent application of these probes as tumor imaging agents and radiosensitizers in tumor detection and radiation therapy were summarized, and application prospects of gold nanoparticles were provided. KEYWORDS Gold nanoparticles, Bioprobes, Tumor detection, Radiotherapy CLC TL13, Q6-33, R815 纳米金颗粒作为一种优异的纳米材料，以其独