化学发光原理与检测项目.ppt

* * * * * * 小剂量抑制试验：午夜11~12时，顿服地塞米松1~2mg(0.75mg×2片)，次晨8时采血，较基础下降50%以上或＜5 ug/dL ，可排除 大剂量抑制试验：在小剂量抑制试验的基础上进行，午夜11~12时，顿服地塞米松8mg(0.75mg×11片)，次晨8时采血，若仍不能抑制则需考虑为肾上腺功能自主性腺瘤或肾上腺腺癌，或异位ACTH综合症，若能抑制，则考虑肾上腺增生可能。 * Claimed 17.5 million lives globally, or 30% of all deaths An estimated 7.6 million died because of coronary heart disease, and 5.7 million due to stroke. Over 80% of CVD deaths occur in low- and middle-income countries Especially due to aging populations, coronary heart disease, and stroke are expected to remain the leading causes of death. * Some Facts about Breast Cancer include: In 2008, the American Cancer Society estimates: Over 67,000 new cases of Carcinoma In Situ Over 180,000 new cases of Invasive cancer North America women have highest rate in the world, but survival rates have been improving * Early detection of cancer is a key to saving lives. As is shown on this slide, an early detection of cancer greatly impacts the 5-year survival rates and the choices physicians have for treatment. Note the significant decrease in survival rates between sequential stages of cancer. For majority of cancers, a 5-year survival is greater than 90% when cancer is detected in stage I and drops significantly during the progression to other stages. The worse survival rates are for pancreatic cancer, with only 40% survival if detected in stage I. We will take a closer look at the pancreatic cancer later. Early detection is often the difference between successful treatment and fatality. The World Health Organization (WHO) estimates that 1/3 of the cancer burden could be reduced with earlier detection. References: /pancreas/BasicIntro.php /docroot/CRI/content/CRI_2_4_1X_What_are_the_key_statistics_for_prostate_cancer_36.asp /mediacentre/factsheets/fs297/en/ * * * 体内因素： 肝肾功能不全和胆汁淤积都可使AFP/CEA等TM升高， 风湿病时可使CA199升高 抗雄激素治疗可抑制PSA产生，直肠指检可使PSA和PAP值升高 体外因素： 来源于肿瘤附近的体液标本可以提高TM检测的阳性率有些TM可因抗原不稳定而在室温下容易降解 微生物感染产生的一些酶可导致CA153分解 * Facts about Prostate Cancer. The statistics for prost