课件：医学统计学精品教学（汕头大学）循证医学临床实践.ppt

* So let’s get started…In groups of 3 or 4 discuss…. Why do we need to write protocols, why not go straight in and so the review? 5 minutes * Level of Evidence Grade of recommendation Grade A: 1a Systematic review (SR) of Randomised Controlled Trials (RCT) 1b individual RCT 1c: All-or-none studies Grade B 2a SR of cohort studies 2b individual cohort study or low-quality RCT(80% follow up) 2c outcome research 3a SR of case-control study 3b individual case-control study Grade C 4 Case series and poor quality cohort/case-control studies Grade D Expert opinion without explicit critical appraisa