基于失匹配负波的大脑功能性网络分析-计算机工程与应用.PDF

64 2016 ，52（20 ） Computer Engineering and Applications 计算机工程与应用 基于失匹配负波的大脑功能性网络分析 1，2 2 3 许学添 ，齐德昱 ，蔡跃新 1，2 2 3 XU Xuetian , QI Deyu , CAI Yuexin 1.广东司法警官职业学院 信息管理系，广州 510520 2.华南理工大学 计算机系统研究所，广州 510006 3.中山大学 孙逸仙纪念医院 耳鼻喉科 听力学与言语研究所，广州 510120 1.Department of Information Administration, Guangdong Justice Police Vocational College, Guangzhou 510520, China 2.Research Institute of Computer Systems, South China University of Technology, Guangzhou 510006, China 3.Institute of Hearing and Speech-Language Science, Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China XU Xuetian, QI Deyu, CAI Yuexin. Brain functional network analysis based on mismatch negativity. Computer Engineering and Applications, 2016, 52 （20 ）：64-68. Abstract ：It establishes a functional brain network according to the Mismatch Negative （MMN ）wave data of normal people and patients with hearing impairment. With calculated the complex networks statistical characteristics of the functional brain network, it finds that the established functional brain network has similar no scaling properties with respect to the random network, but also has high clustering coefficient, small characteristic path lengths of small world network charac- teristics. In addition, the average degree of functional network and network structure entropy are calculated. The results show that the average degree, clustering coefficient and structure entropy of the functional network are higher than those of the patients with hearing impairment. It indicates the reduction of functional connectivity after hearing loss may contribute to the decreased spatial discrimination. The functional network parameters of average degree, clustering coefficient and network structure entropy may be considered as the central markers with reflecting th