淋巴细胞主动免疫联合静滴丙种球蛋白治疗复发性流产56例疗效分析.pdf

13 9 河 北 医 学 Vol. 13, No. 9 2007 9 HEBEIMED ICINE Sep. , 2007 : 1006- 6233( 2007) 09- 1078- 03 56 梁宝珠, 谭忠伟, 黄显文, 王 梅 (广东省江门市妇幼保健院, 广东 江门 529000) :: 探讨淋巴细胞主动免疫联合静滴丙种球蛋白治 复发性流产的临床 效: 将经临床筛查确诊为封闭抗体缺乏所致的复发性流产患者 56例随机分为两组, 一组 34例为研究组, 采用淋巴细胞主动免疫联合静滴丙种球蛋白治 , 另一组 22例为对照组, 采用传统保胎治 (黄体酮 加HCG), 观察 效及妊娠结局: 研究组妊娠成功率 91. 18%, 对照组妊娠成功率 40. 91% , 差异 有显著性( P 0. 01) : 淋巴细胞主动免疫治 联合静滴丙种球蛋白治 复发性流产成功率较 高, 有较可靠的应用价值 : 淋巴细胞; 丙种球蛋白; 免疫治 ; 复发性流产; 封闭抗体 : R714. 21 : B The Analysis of Rec rrent Spontaneo sAbortion Under the Treatment of Imm notherapy with Lymphocytes and Imm ne Globalin Intraveno s( IVIG) L IAN G B ao- zhu, TAN Zh ong -w ei, H UAN G X ian -w en, et a l ( J iangm en M a tern ity and Ch ild H ea lth Care H osp ita l, G uangd ong J iangm en 529000, Ch ina) Abstract: Objective: To investigate t e effection of mi munot erap y w it lymp ocytes and mi mune globulin intravenous( IV IG) in w omen w it recurrent spontaneous abortion. M ethod: 56 patients diagnosed as recurrent spontaneous abortion cause of lack ing block ing antibodiesw ere d ivided into wt o groups: 34 ca- ses as group of mi munot erapy w it lymp ocytes and IV IG( control group) , anot er 22 casesw it HCG and progesteron ( comparison group ). Res lt: T e pregnancy and carrying rate s ow ed : 91. 18% in control group and of its s ow ed only 40. 91% in t e comparison group. Concl sion: Immunot erapy w it lymp o- cytes and IV IG may act as an effective and safe met od for treatment recurrent spontaneous abortion. Key words: Lymp ocytes; IV IG; Immunot erapy; R ecurrent spontaneous abortion; Blocking