左外侧裂后部经颅直流电刺激对失语症图命名及听-中国康复医学杂志.PDF

2011年，第26卷，第10期 ·临床研究· 左外侧裂后部经颅直流电刺激对失语症图命名及 听理解作用的研究* 1 1,2 1 1 汪 洁 吴东宇 宋为群 袁 英 摘要 目的：探查恢复期失语症患者左外侧裂后部（PPR）经颅直流电刺激（tDCS）对图命名及听理解的作用。 方法：采用成组前后对照实验设计，治疗分为A、B期。A期为4周语言治疗，B期为4周tDCS治疗与语言治疗。tDCS 刺激电极阳极位于左侧外侧裂后部周围区，阴极位于右肩。刺激强度1.1mA，每次20min。7例脑卒中后失语症患者 在每个治疗期前后进行汉语失语症心理语言评价（PACA）。 结果：7例患者经4周A期语言治疗后，图命名和听觉词—图匹配成绩未见显著改变；经4周tDCS与语言治疗后，患 者的图命名和听觉词—图匹配成绩显著提高（图命名成绩平均提高64%，听觉词—图匹配成绩平均提高15%）。 结论：tDCS阳极刺激左外侧裂后部周围区可以提高恢复期失语症患者的图命名和听觉词—图匹配任务的正确率， 其治疗机制可能是由于阳极刺激提高了脑损伤周围区的神经元兴奋性，促进了语言功能的代偿。tDCS为失语症提 供了一种新的有效的治疗技术。 关键词 图命名；听理解；失语症；经颅直流电刺激 中图分类号：R454.1 文献标识码：A 文章编号：1001-1242（2011）-10-0921-04 Effects of transcranial direct current stimulation over left posterior perisylvian region on picture naming and auditory word comprehension in aphasia/WANG Jie, WU Dongyu, SONG Weiqun, et al.//Chinese Journal of Rehabilitation Medicine, 2011, 26(10): 921—924 Abstract Objective: To investigate the effects of transcranial direct current stimulation（tDCS）over left posterior perisylvian region(PPR)onaphasics picturenamingand auditoryword comprehension. Method: Treatment procedure was divided into phase A and phase B. First routine four-week language training (30min 0d and 5d a week) was applied in phase A, then routine language training combined with tDCS (1.1mA, 20min) were implemented in phase B. Anode electrode was placed over PPR, while cathode electrode over right shoulder in tDCS treatment. Seven aphasia subjects after stroke were measured with psycholinguistic assessment in Chineseaphasia(PACA) before andafter each treatmentphase. Result: There was no significant change in picture naming and auditory word-p