罗宾基础病理学ppt课件 注解-Ch6-Immune.pptVIP

* Why is amyloid called amyloid? Because in the early days, it took up STARCH stains applied to GROSS specimens, e.g., IODINE stains. But of course now we know it’s a PROTEIN, chiefly immunoglobulin protein chronic buildup. It is therefore not surprising that diseases which have chronic immunoglobulin buildup over many years are associated with amyloidosis, i.e., multiple myeloma (also called plasma cell “dyscrasias”), granulomatous diseases, classically. * Apple green birefringence under polarized light of congo red stained amyloid is DIAGNOSTIC of amyloidosis. Apple green birefringence under