含NADH模型的金属-有机大环催化性质研究-精细化工专业论文.docxVIP

含M址)H模型的金属一有机大环催化性质研究The 含M址)H模型的金属一有机大环催化性质研究 The Metal—o略anic Macrocycle C0ntailling NADH Model for CataMic Research Abstract ’I’he enzyme m hfe which ls one kind of proteins llas high cat蝴ic e伍ciency，but the em：yme孙actiVe material isⅥllnerdble to inactivation by en、，ironmental factors．Since 1 978， Professor Lehn J．M．pr叩osed supr锄olecular chenlistry t11eo巧，using sup埘n01ecular ch耐s仃y theory to solve the p∞blems a：bout the syn血esis of a而丘cial em可mes has dIaWn increaSing interest in sWIramolecular che血sts．SmaU缸d complementary Inolecules c衄be made to recognize each omer nlrough nonco砌ent interactiolls跚ch as hydrogen bo血Iing， charge—charge，dono卜acc印tor，兀-兀，锄d van der Waals，etc．Such“pro哥砒Imed’’molecules can mus be semaLssenlbled by utilizing these interactions in a de血ite algo—thm to fo珊large supr锄01ecules that have憾rent physicochl疵cal propemes th王m those of the precursor building blocks．Typical syste黜are desigIled so that协e self-勰s锄bly process is kineticauy re、，ersible；也e indi访dual building blocks gr础lauy如nnel tow龇．d an enseIIl_ble that represents theⅡle册odynamic min证mm of the system、，ia n珊nerous舔sociation and dissociation st印s． By tuniI垮V撕ous reaction pa您meters，the reaction equjlibmm can be shjfted toward me desired product．As such，se妊assenlbly has a distinct adV卸tage over tr砌tional，step谢se synthetic approaches when accessing 1a唱e m01ecules．ourrently，gupramolecular ch锄is仃y has a wide range of applications i11 m01ecular recog血ion，catalysis，storage and other fields． De一诎lg铆。硼m№姐ds of tridentate NNO coor血ation sites也rou曲Schif!F base reaction，coordination、Ⅳith由∞sition metal Ni ion self-as∞mbly，Ni．ZPB Inetal．organic four-meIll：ber ring smlc慨is obtained．Ru(bpy)3(PF6)2 wo r：ks as photosensitizer，硒corbic acid works舔electron sacrificial agent，Ni-ZPB works舔c删vst to model a hvdrogenase iIl nature cata研ic center stmctllre，to achieVe light—d矗Ven hydrogen product research．Ni-ZPB cont蛐g dihydropyridine amide group呻roVes elector tra越t-er rate，so that it ma】(es the 、Ⅳhole hydrogen pro