汉字心理旋转的皮层相互作用网络-生物医学工程专业论文.docxVIP

IV IV 试图利用基于脑电信号的多通道自回归模型，研究汉字心理旋转下的 皮层相互作用网络。 本研究中，我们设计汉字心理旋转实验，旋转角度分别为 0°、 ±60°、±120°和 180°，并采集 9 名志愿者的头皮脑电信号（男 女比为 6：3）。我们利用基于多变量格兰杰因果性的 PDC 分析方法， 来分析皮层之间的相互作用关系。我们发现，在±60°和±120°情 况下，不论是在顶叶还是运动皮层，侧向的脑半球间作用关系都表现 为从右到左，而且随角度的增加而加强。顶叶和运动皮层之间的主要 相互作用，在±60°和±120°下是向前的；但在±120°时，出现了 这两个皮层间双向的作用关系。对于 180°，运动皮层的侧向相互关 系消失，同样消失的还有顶叶与运动皮层之间的双向作用。这些发现 揭示在汉字心理旋转情况下：（1）随着任务要求的变化，皮层相互作 用网络是变化的；（2）在两侧半球的活动中，右脑担负着“起始”的 角色。 关键词：皮层相互作用网络；心理旋转；汉字；脑电信号 PAGE PAGE VI Cortical Interactive Networks under Mental Rotation of Chinese Character ABSTRACT Mental rotation (MR), originally proposed by Shepard and Metzler, has been a well-known cognitive experiment for decades in mental spatial imagination. In MR tasks, subjects were shown rotated figures and asked to discriminate whether the figures were identical or enantiomorphous. And it was found that subjects needed more time to respond with the increase of the angular disparity[58]. For decades, abundant studies attempted to interpret the psychophysical mechanisms underlying MR. Cognitive process of MR is associated with multi-component neural networks. The most significant work is about the cortical network, and researchers have come to an agreement on distributed neural systems involved in MR, comprising parietal and motor-related areas. However, by far few literatures have reported the cortical interactive network under MR, and some papers proposed plausible cortical connections according to the sequential order of neural activations. Recent work also suggested that the cortical connections under MR were dependent on task-difficulty. Moreover, some researchers speculated MR of Chinese character employed distinct strategies and cortical interactive networks depending on the task difficulty, which is subjected to validation by more neurophysiologic evidences. Therefore, the analysis of cortical interactions helps to interpret the cognitive process of Chinese character MR. Neural engineers have proposed a variety of quantitative electro