临床指南：呼吸科-2014 ATS／ERS共识：慢性阻塞性肺病四肢肌肉功能障碍（更新版）全文.pdfVIP

AMERICAN THORACIC SOCIETY DOCUMENTS An Official American Thoracic Society/European Respiratory Society Statement: Update on Limb Muscle Dysfunction in Chronic Obstructive Pulmonary Disease François Maltais, Marc Decramer, Richard Casaburi, Esther Barreiro, Yan Burelle, Richard Debigare,´ P. N. Richard Dekhuijzen, Frits Franssen, Ghislaine Gayan-Ramirez, Joaquim Gea, Harry R. Gosker, Rik Gosselink, Maurice Hayot, Sabah N. A. Hussain, Wim Janssens, Micheal I. Polkey, Josep Roca, Didier Saey, Annemie M. W. J. Schols, Martijn A. Spruit, Michael Steiner, Tanja Taivassalo, Thierry Troosters, Ioannis Vogiatzis, and Peter D. Wagner; on behalf of the ATS/ERS Ad Hoc Committee on Limb Muscle Dysfunction in COPD THIS OFFICIAL STATEMENT OF THE AMERICAN THORACIC SOCIETY (ATS) AND THE EUROPEAN RESPIRATORY SOCIETY (ERS) WAS APPROVED BY THE ATS BOARD OF DIRECTORS, NOVEMBER 2013, AND BY THE ERS EXECUTIVE COMMITTEE , SEPTEMBER 2013 Background: Limb muscle dysfunction is prevalent in chronic Results: We identified important advances in our understanding obstructive pulmonary disease (COPD) and it has important clinical of the extent and nature of the structural alterations in limb muscles implications, such as reduced exercise tolerance, quality of life, in patients with COPD. Since the last update, landmark studies and even survival. Since the previous American Thoracic Society/ were published on the mechanisms of development of limb muscle European Respiratory Society (ATS/ERS) statement on limb dysfunction in COPD and on the treatment of this condition. We muscle dysfunction, important progress has been made on the now have a better understanding of the clinical implications of limb characterization of this problem and on our understanding of its muscle dysfunction. Although exercise training is the most potent pathophysiology and clinical implic