磁共振扩散加权成像在肝癌化疗栓塞术后疗效评价中的-中国癌症杂志.PDF

中国癌症杂志 2015年第25卷第4期 《 》 CHINA ONCOLOGY 2015 Vol.25 No.4 311 磁共振扩散加权成像在肝癌化疗栓塞术 后疗效评价中的应用 杨欢，李文涛，许立超 复旦大学附属肿瘤医院介入科，复旦大学上海医学院肿瘤学系，上海 200032 　　［摘要］　经导管肝动脉化疗栓塞术(transcatheter arterial chemoembolization，TACE)是临床不可切除肝癌的 主要治疗方法，扩散加权成像(diffusion weighted imaging，DWI)作为一种无创的MRI功能成像，能先于肿瘤形态 学改变，观察到肿瘤的功能改变，在肝癌化疗栓塞术后的随访中，能够及时、准确地检测到肝内新发病灶，鉴 别肿瘤组织的坏死和残留。 　　 ［关键词］　肝癌；扩散加权成像；经导管动脉化疗栓塞；表观弥散系数；随访 　　DOI: 10.3969/j.issn.1007-3969.2015.04.012 R730.44 R735.7 A 1007-3639(2015)04-0311-05 　　 中图分类号： ； 　　文献标志码： 　　文章编号： The value of MR diffusion-weighted imaging in the assessment of tumor response after TACE in patients with hepatocellular carcinoma YANG Huan, LI Wentao, XU Lichao (Department of Interventional Therapy, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China) Correspondence to: LI Wentao E-mail: liwentao@126.com Abstract Transcatheter arterial chemoembolization (TACE) is the main treatment method for advanced 　　［ ］ hepatocellular carcinoma (HCC). As a non-invasive functional MR imaging, diffusion weighted imaging (DWI) can reflect the functional changes in tumor before morphologic changes. In the follow-up of HCC after TACE, DWI can detect new lesions and distinguish necrotic neoplastic tissue and residual neoplastic tissue timely and accurately. Key words Hepatocellular carcinoma; Diffusion weighted imaging; Transcatheter arterial chemoembolization; 　［ ］ Apparent diffusion coefficient; Follow-up (hepatocellular carcinoma HCC) 的重要保证。 　　原发性肝癌 ， 是严重危及人类健康的常见恶性肿瘤之一，居全