己治愈单眼弱视患者多焦视觉诱发电位的研究-临床医学;眼科学专业论文.docxVIP

天津医科大学硕士学位论文中文摘要 天津医科大学硕士学位论文 中文摘要 目的评价已治愈的单眼弱视患者多焦视觉诱发电位(multifoeal visual evoked potential，mfVEP)的恢复情况。 方法记录32例6--15岁已治愈的单眼弱视(斜视性弱视、屈光参差性弱 视或斜视性弱视合并屈光参差性弱视)患者及30例7～17岁正常人多焦视觉诱 发电位，．分别比较已治愈单眼弱视患者弱视眼、对侧眼及正常人三组之间上、 下半视野不同离心度(1环、2环、3环、4环)多焦视觉诱发电位特征峰P波 的潜伏期及振幅密度。 结果弱视眼上、下半视野1环、2环、3环、4环特征峰P波潜伏期及振幅 密度较对侧眼差别均无统计学意义(PO．05)；弱视眼和对侧眼上、下半视野1 环、2环、3环、4环的特征峰P波潜伏期均较正常组显著延长·，差别有统计学 意义(尸n05)，而振幅密度较正常对照组差别无统计学意义(PO．05)。 结论1．己治愈单眼弱视患者，随着视力恢复至正常水平，弱视眼的上、下 半视野四个离心度mfVEP特征峰P波潜伏期和振幅密度可恢复至与对侧眼相当 水平。 2．已治愈单眼弱视患者弱视眼和对侧眼的上、下半视野四个离心度mfVEP 特征峰P波潜伏期和振幅密度虽然无显著差别，但弱视眼、对g,tl艮分别与正常 人比较时，它们的潜伏期仍较正常人延长，说明已治愈单眼弱视患者弱视眼和 对侧眼的传导通路及视皮层仍存在异常。 3．已治愈单眼弱视患者弱视眼和对侧眼的上、下半视野四个离心度mfVEP 特征峰P波振幅密度与正常人比较，三组之间的差别无统计学意义，表明已治愈 的单眼弱视患者的mfVEP的振幅密度较潜伏期提前恢复至正常人水平。 关键词：单眼弱视治愈多焦视觉诱发电位 天津医科大学硕士学位论文Abstract 天津医科大学硕士学位论文 Abstract Purpose To assess multifocal visual evoked potential(mfVEP)recovery in successfully treated monocular amblyopes． Methods MWEP were recorded from 32 successfully treated monocular amblyopes(strabismic arnblyopia,anisometropic amblyopia and combined strabismic and anisometropic amblyopia)6 to 1 5 years of age and 30 normal children 7 to 1 7 years of age．The latency and amplitude density of P waves from different eccentric rings(1 ring，2ring，3ring，4ring)in amblyopic eyes was compared with the fellow eyes and normal eyes． Results Comparison between the amblyopic and the fellow eyes showed no significant difference in the latency and amplitude denSity of P waves from different eccentric rings in both upper and lower hemifields(PO．05)；The latency of P waves from four eccentric tings in both upper and lower hemifields were prolonged in comparison with amblyopic eyes and normal eyes，and the same result Was found between fellow eyes and normal eyes(Pn D5)．The amplitude density of P waves from four eccentric rings in both upper and lower hemifields were no significant difference in comparison with amblyopi9 eyes and normal eyes，and that the same result was found between fellow eyes and normal eyes(PO．05)． Concl