加味黄芪建中汤加减治疗腹泻型肠易激综合征脾气虚型的临床观察-中医内科学专业论文.docxVIP

成都中医药大学硕士学位论文 成都中医药大学硕士学位论文 I I 中文摘要 目的：通过对加味黄芪建中汤加减方的临床研究和观察，探讨加味黄芪建中汤加 减治疗腹泻型肠易激综合征（脾气虚型）的临床疗效及安全性。 方法：将成都中医药大学附属医院干部内科门诊 60 例的腹泻型肠易激综合征（脾 气虚型）患者随机分为治疗组和对照组。治疗组、对照组各 30 例患者，治疗组 予以加味黄芪建中汤加减口服治疗，对照组给予匹维溴铵片治疗。治疗期间均停 用其他药物，疗程 4 周，停药 2 周，比较治疗前后两组的临床症状改善程度，对 其做出疗效及安全性评价。 结果：治疗组有效率为 90%，对照组的有效率为 76.7%，经统计学分析两组治疗 前后各项指标差异均有统计学意义（P0.05）。说明加味黄芪建中汤加减治疗脾 气虚型腹泻型肠易激综合征的总体疗效大于匹维溴铵片（得舒特）。 结论：加味黄芪建中汤加减治疗腹泻型肠易激综合征（脾气虚型），能显著改善 患者腹泻、腹痛等相关临床症状和生活质量，并未见不良反应，治疗安全有效。 关键词：加味黄芪建中汤 腹泻型肠易激综合征 临床观察 II II Abstract Objective: To investigate the effect and safety of using Jiawei huangqi jianzhong tang with modification treatment of diarrhea-irritable bowel syndrome (pi qi xu type) . Methods: The 60 patients with diarrhea-irritable bowel syndrome (pi qi xu type) from Hospital of Chengdu University of TCM were randomly divided into treating groups and controlling group, 30 patients in treating group, the treating group was treated by decoction of Jiawei huangqi jianzhong tang with modification oral treatment, the control group was treated by Horse dimension bromine ammonium piece together ,are disabled during treatment with other drugs,four-week course of treatment, drug two weeks before and after treatment were compared between two groups improvement of clinical symptoms, to evaluate the efficacy and safety. Results: The effective rate of the treating group is 90%, the control groups effective rate is 76.7%,by statistical analysis of the overall efficacy of the two groups were significantly different (P 0.05). Conclusion: Jiawei huangqi jianzhong tang with modification treatment of patients with diarrhea-irritable bowel syndrome can significantly improve the clinical symptoms and the quality of life, and no side effects, treatment is safe and effective. Key words: Jiawei huangqi jianzhong tang Diarrhea-irritable bowel syndrome Clinical observation PAGE PAGE IV （英文）缩略词表 缩略词 英文全称 中文 A-IBS Alternating-Irritable Bowel Syndrome 便秘腹泻交替型肠易激综合征 CCK