加味黄芪建中汤治疗灼口综合征（脾阳气虚证）的临床疗效观察-中西医结合临床专业论文.docxVIP

万方数据 万方数据 中文摘要 目的：观察加味黄芪建中汤治疗脾阳气虚证灼口综合征的安全性及疗效。 方法：采用随机、对照的试验方法，用 spss17.0 生成随机数字表，将 60 例符合研究标准的灼口综合征患者，随机分为对照组和治疗组各 30 例进行研究。 对照组服用多维元素片，治疗组服用加味黄芪建中汤，疗程均为 8 周。选取治疗 前后视觉模拟评分、中医证候积分等为观察指标，观察加味黄芪建中汤的安全性 及疗效。所得数据符合正态分布及方差齐性，采用 t 检验进行统计分析；不符合 者采用秩和检验进行统计分析；计数资料采用卡方检验；等级资料采用秩和检验。 结果：（1）治疗组临床总有效率 71.42%,对照组总有效率 50.00 %，治疗组 优于对照组（P＜0.05）；（2）治疗组中医证候疗效总有效率 82.14%，对照组总 有效率 40.00%，治疗组优于对照组（P＜0.05）；（3）治疗组及对照组均未见明 显不良反应。 结论：加味黄芪建中汤能有效缓解灼口综合征患者的疼痛及改善中医临床证 候，疗效较好且使用安全。 关键词：灼口综合征 脾阳气虚 加味黄芪建中汤 温阳健脾 气机 Abstract Objective: To observe the safety and efficiency of the modified Huangqi Jianzhong Tang adopted to treat burning mouth syndrome which belongs to Spleen-yang and qi deficiency syndrome. Methods: Randomized and controlled trial methods were applied in the research. Using spss17.0 to generate random Numbers table, 60 patients who met the research standard of BMS were divided randomly into control group and treatment group with 30 patients respectively .Multivitamin and mineral tablets were employed by the control group and the Huangqi Jianzhong Tang for the treatment group. Both groups were observed for 8 weeks. The safety and efficiency was evaluated by comparing the VAS scores and TCM syndrome integral before and after the treatment. The data which conforms to normal distribution and branch homogeneity was dealt with t test statistical analysis, otherwise, it was analyzed by rank sum test ; count data by chi-square test; level data by rank sum test . Results：(1) The total effective rate for the treatment group is 71.42%; the control group total effective rate is 50.00%, the treatment group total effectiveness prevailed the control group (P 0.05). (2)The total effective rate of TCM syndrome in treatment group is 82.14%, while for the control group, it is 40.00%，so the treatment group total effectiveness is better than the control group (P 0.05). (3) The treatment group and control group had no obvious adverse reactions. Conclusion: the modified Huangqi Jianzhong Tang can effec