几类具有生物活性配合物的合成、表征及生物活性研究-无机化学专业论文.docxVIP

PAGE PAGE 10 种金属的配合物晶体 Nd(Phen)2(NO3)3 为单核结构 晶体属单斜晶系 Cc 空间群 晶胞参数 : a=11.1975(17), b=18.073(3), c=13.095(2) ?, a=100.584(3) ° , Z=4, Dc=1.761mg/m3, V=2605.1(7) ?3 晶体结构表明 配合物中心金属 Nd( )为十配位 和配体形成一个歪曲的双帽四方反棱柱体 第二颗晶体为双核结构 晶体属三斜 晶系 P-1 空间群 晶胞参数: a=12.063(3), b=12.967(3), c=13.260(3) ?, á =104.046(4), a=113.750(4), ?=100.391(4)° , Z=1, Dc=1.8416 mg/m3, V=1749.0 (8) ?3 羧基与 Sm ( ) 以两种方式结合 桥式双齿和桥式三齿 Sm ( )为九配位 几何构型为畸变的三 帽三角棱柱体 关键词 过渡金属配合物 稀土配合物 2-氨基苯并噻唑 氨基酸席夫碱 8- 羟基喹啉 3 5 二硝基苯甲酸 晶体结构 生物活性 Synthesis, Crystal Structure and Bioactivity Research of Three Series of Complexes with Antibacterial Activity Abstract Three series of complexes which have antibacterial activity have been synthesized and characterized by elemental analysis, IR, UV, fluorescent spectra and single crystal X-ray diffraction analysis. The first series of complexes is three unprecedented compounds Zn(C7H6N2S)2(CH3COO)2(1), Ag(C7H6N2S)(NO3)(2), Cu-(Sal-Gly)-(C7H6N2S) (3). In compound 1,the Zn tom is four-coordinated by one N atom from each of two 2-aminobenzothiazole ligands and one O atom from each of two monodentate acetate anions, this ZnO2N2 coordination forms a distorted tetrahedral geometry with a local non-crystallographic C2 symmetry . The amino groups act as donors in N H O hydrogen bonds, two intermolecular N H O hydrogen bonds interconnect the molecules into a three-dimensional network. Compound 2 belongs to monoclinic crystal system. The X-ray diffraction analysis reveals that the compound is mononuclear with space group P2(1)/c, the Ag ion is two-coordinated with one O atom from NO3- and N atom from 1,3-thiazole ligand. Complex 3 is the ternary complexes of transition metal Cu with tridentate Schiff base derived from amino acid(Gly) and 2-aminobenzothiazole. The schiff base(Sal-Gly) is obtained from the reaction salicylidene and glycine. X-ray crystal stucture analysis revealed the complex 3 is a mononuclear molecule