高通量滤器干预维持血液透析患者后血清钙、磷、.docVIP

高通量滤器干预维持性血液透析患者后血清钙、磷、甲状旁腺激素的变化分析 Serum calcium, phosphorus, parathyroid hormone change analysis after the intervention of high-throughput filter hemodialysis patients 石丽丽 王夏莲 西安市华山中心医院 710032 Xian Huashan Central Hospital 710 032 摘要：目的：探讨高通量滤器干预维持性血液透析患者后钙、磷以及甲状旁腺的变化。方法：将48例维持血液透析患者改用高通量滤器透析治疗3个月，其中2014年3月前采用低通量滤器干预干预维持血液透析患者作为低通量组（n=48），2014年3月后采用滤器干预干预维持血液透析患者患者作为高通量组（n=48）。比较两组血清钙、血清磷、全段甲状旁腺素(intact parathyroid hormone，iPTH)水平的差异。结果：与低通量滤器透析患者比较，高通量组患者血钙显著升高，差异具有统计学意义(P＜0.05)，血磷、甲状旁腺素水平明显降低，差异具有统计学意义(P＜0.05)， 高通量组血清钙2.10～2.50mmol/L、血清磷0.81～1.45mmol/L、iPTH 130～600ng/L达标控制率显著高于低通量组，差异具有统计学意义（P0.05）。结论：高通量滤器透析能够有效改善尿毒症维持血液透析患者钙、磷、甲状旁腺代谢紊乱，值得在临床中推广应用。 Abstract: Objective: To maintain high throughput filter change after the intervention in hemodialysis patients, calcium, phosphorus and parathyroid. Methods: 48 patients on maintenance hemodialysis patients switched to high-throughput filter dialysis treatment three months, Before March 2014 using the intervention of low-throughput filter hemodialysis patients were as low-throughput group (n = 48), after March 2014 using the intervention of high-throughput filter hemodialysis patients were as high-throughput group(n = 48),the difference of serum calcium, serum phosphorus, intact parathyroid hormone(iPTH) levels between the two groups were compared.Results: Compared with patients with low-throughput group,serum calcium of patients with high-throughput group were significantly increased, the difference was statistically significant (P 0.05), serum phosphorus, intact parathyroid hormone levels were significantly lower, the difference was statistically significant (P 0.05), serum calcium 2.10～2.50mmol/L,serum phosphorus 0.81～1.45mmol/L,iPTH 130～600ng/L standard control rate were more significant than in low-throughput group, the difference was statistically significant (P 0.05). Conclusion: The high-throughput filter can improve dialysis uremic hemodialysis patients calcium, phosphorus, parathyroid metabolic dis