2019ASH临床实践指南:应用促红细胞生成类药物治疗癌症相关贫血.pdf

2019ASH临床实践指南:应用促红细胞生成类药物治疗癌症相关贫血.pdf

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CLINICAL GUIDELINES Management of cancer-associated anemia with erythropoiesis-stimulating agents: ASCO/ASH clinical practice guideline update Julia Bohlius,1,* Kari Bohlke,2 Roberto Castelli,3 Benjamin Djulbegovic,4 Maryam B. Lustberg,5 Massimo Martino,6 Giannis Mountzios,7 8 9 10 ` 11 12 13, Namrata Peswani, Laura Porter, Tiffany N. Tanaka, Gianluca Trifiro, Hushan Yang, and Alejandro Lazo-Langner * 1University of Bern, Bern, Switzerland; 2American Society of Clinical Oncology, Alexandria, VA; 3University of Milan, Milan, Italy; 4City of Hope, Duarte, CA; 5Ohio State University, Columbus, OH; 6Azienda Ospedaliera Bianchi Melacrino Morelli, Reggio Calabria, Italy; 7Henry Dunant Hospital Center, Athens, Greece; 8Advocate Medical Group, Orland Park, IL; 9Independent Patient Advocate, Washington, DC; 10UC San Diego Moores Cancer Center, La Jolla, CA; 11University of Messina, Messina, Italy; 12Thomas Jefferson University, Philadelphia, PA; and 13Western University, London, ON, Canada Purpose: To update the American Society of Clinical Oncology (ASCO)/American Society of Hematology (ASH) recommendations for use of erythropoiesis-stimulating agents (ESAs) in patients with cancer. Methods: PubMed and the Cochrane Library were searched for randomized controlled trials (RCTs) and meta-analyses of RCTs in patients with cancer published from January 31, 2010, through May 14, 2018. For biosimilar ESAs, the literature search was expanded to include meta-analyses and RCTs in patients wi

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