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睡眠檢查判讀可信度研討會摘要
International Agreement in Sleep and Respiratory Scoring
陳 濘宏醫師
Study Objectives: The American Academy of Sleep Medicine (AASM) guidelines
for polysomnography (PSG) scoring are increasingly being adopted worldwide, but
the agreement among international centers in scoring respiratory events and sleep
stages using these guidelines is unknown. We sought to determine the interrater
agreement of PSG scoring among international sleep centers.
Design: Prospective study of interrater agreement of PSG scoring.
Setting: Nine center-members of the Sleep Apnea Genetics International Consortium
(SAGIC).
Measurements and Results: Fifteen previously recorded deidentified PSGs, in
European Data Format, were scored by an experienced technologist at each site after
they were imported into the locally used analysis software. Each 30-sec epoch was
manually scored for sleep stage, arousals, apneas, and hypopneas using the AASM
recommended criteria. The computer-derived oxygen desaturation index (ODI) was
also recorded. The primary outcome for analysis was the intraclass correlation
coefficient (ICC) of the apnea-hypopnea index (AHI). The ICCs of the respiratory
variables were: AHI = 0.95 (95% confidence interval: 0.91-0.98), total apneas = 0.77
(0.56-0.87), total hypopneas = 0.80 (0.66-0.91), and ODI = 0.97 (0.93-0.99). The
kappa statistics for sleep stages were: wake = 0.78 (0.77-0.79), nonrapid eye
movement = 0.77 (0.76-0.78), N1 = 0.31 (0.30-0.32), N2 = 0.60 (0.59-0.61), N3 =
0.67 (0.65-0.69), and rapid eye movement = 0.78 (0.77-0.79). The ICC of the arousal
index was 0.68 (0.50-0.85).
Conclusion: There is strong agreement in the scoring of respiratory events among the
SAGIC centers. There is also substantial epoch-by-epoch agreement in scoring sleep
variables. Our results suggest that centralized scoring of PSGs may not be necessary
in future research
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