抗真菌药物临床应用及市场分析-制药工程专业毕业论文.docxVIP

4 4 t只军 硕士学位论文 药。临床工作者应在全面了解患者情况后，选择最合适的药物或联合用药，使真菌 感染病的治疗更经济有效。我们应进一步加强宏观管理，使抗真菌药物的应用更 趋合理。进入2l世纪，真菌基因组学、生物信息学和遗传学工具的实用性不断提 高，在与顽固性真菌感染的斗争中，这些进展无疑将发挥重要作用。 关键词：真菌感染；抗真菌药物；临床应用；市场分析 2 厶f 厶f z g 硕士学位论文 CLINICAL APPLICATIoN oF ANTIFUNGAL DRUGS AND ITS MARKET ANALYSIS Postgraduate：Li Chun—Hong Supervisor：Guo Xiu-Li ABSTRAC T Objective：With the extensive application of broad-spectrum antibiotics， corticosteroids and immunosuppressant and the usage of advanced technologies，such as the promotion of organ transplants， aS well as tumor chemotherapy and radiotherapy,the impact of fungal infections both in the frequency or in the area of pathogenic bacteria al e constantly increase in recent years．Antifungal drug has become one of most important anti—infective drugs in clinical use and the huge amount of the OTC application．Introduce the progress on the development of antifungal drug and clinical application of the fiend through investigation of the clinical application of antifungal agents and their market analysis is essential for clinical workers，simultaneously providing more drug information against fungal infections to patients，consequently elucidating further antifungal application of the rational and standardized management of scientific theory． Methods：This study is mainly based on the data of domestic economy authoritative medical information of hospital antifungal market and the clinical application from 200 1 to 2005 on Web site．as well as domestic and foreign medical literature review and analysis，and the actual antifungal prescription analysis of some of the hospital in Zibo City from 2006 to 2007． Results and Conclusions：At present，antifungal drugs that act on the fungal cell membrane and nucleic acid still hold the vast majority of the market． With the widely use of these two types of traditional drugs，drug resistance is a conlnlon 3 厶3|}只善 厶3|}只善 硕士学位论文 皇昔詈暑皇昌葛葛昌暑暑暑宣穹鲁昔詈暑暑詈詈詈詈詈詈詈詈=詈詈詈詈詈詈詈詈詈詈詈詈|鲁皇葛昌皇=皇警喜=暑=皇暑=詈詈詈詈詈=詈詈詈詈詈詈詈詈詈兰!詈皇皇詈鼍昌晕置皇皇昔篁量暑墨詈暑詈暑置,i,