汕头大学医学院药理学精品课程 Sedative-Hypnotic Drugs.pptVIP

Sedative-Hypnotic Drugs Department of Pharmacology Zhang Yanmei Normal sleep consists of distinct stages,based on three physiologic measures: the electroencephalogram, the electromyogram, and the electronystagmogram. Non-rapid eye movement(NREM) sleep: 70%-75% Stage 1,2 Stage 3,4:slow wave sleep, SWS Rapid eye movement(REM) sleep BASIC PHARMACOLOGY OF SEDATIVE-HYPNOTICS An effective sedative (anxiolytic) agent should reduce anxiety and exert a calming effect with little or no effect on motor or mental functions. A hypnotic drug should produce drowsiness and encourage the onset a