蒙特利尔认知评估量表对女性抑郁症患者认知功能障碍评估的初步研究.docVIP

蒙特利尔认知评估量表对女性抑郁症患者认知功能障碍评估的初步研究 杨旻实 (沈阳市精神卫生屮心 110168) 【摘要】目的：观察北京版蒙特利尔认知评估量表(Montreal Cognitive Assessment Scale, MoCA)对女性抑郁症患者认知功能障碍的评定效果，并对其标 准效度进行检验。方法：应用简易智能状态检查量表(Mini—Mentalstate Examination, MMSE)和MoCA分别对实验组(49例女性抑郁症患者)和对照组(47 例健康女性)进行认知功能评估，实验组给予对应临床治疗，并于8周后再次进 行MMSE和MoCA评估。结果：对照组和实验组患者治疗前后MoCA与MMSE 总分均具有较好相关性(r=0.901, r=0.892, r=0.871, Plt;0.05)。实验组治疗前后 MoCA各分测验得分及总分较对照组有差异，具有统计学意义(Plt;0.05),实验 组患者治疗后8周，除延迟记忆、抽象、视空间执行功能外，较治疗前MoCA各 分测验得分及总分明显提高，具有有统计学意义(Plt;0.05)o实验组治疗前MoCA 检出率明显高于MMSE检出率，差异有统计学意义(chi;2二5.63,Plt;0.05)。结论： MoCA在临床屮筛查女性抑郁症患者的认知功能障碍具有可靠的标准效度，与 MMSE比较，MoCA对于筛查女性抑郁症患者的认知功能障碍有较好的敏感性。 【关键词】女性抑郁症认知功能蒙特利尔认知评估量表简易智能状 态检查量表 【中图分类号】R749 【文献标识码】A 【文章编号】1672-5085 (2014) 07-0166-02 【Abstract ] Purpose:Observe the Beijing edition of the Montreal Cognitive Assessment (Montreal Cognitive Assessment Scale, MoCA) on cognitive dysfunction in female patients with depression assessment results, and to test the validity of its sta ndards.Method:applicati ons Mini Men tai State Exami nation Scale(Mini-MentalState Examination,MMSE),and MoCA were the experimental group(49 cases of women with depression) and control group (47 cases of healthy wome n) to assess cogn itive function corresponding to the experime ntal group were given clinical treatment and at 8 weeks after the MMSE and MoCA assessment again.Results:The patients in the control group and the experimental group before and after treatment MoCA and MMSE scores were correlated with good (r = 0.901,r=0.89乙r=0.871,Plt;0.05).MoCA experimental group before and after treatme nt, and the total score for each subtest score d iff ere nces compared with the control group, with statistical significanee (Plt;0.05), patients in the experimental group after 8 weeks of treatment,in addition to delay edmemor^abstractio n’visuospatial executive function compared with treatme nt MoCA before each subtest scores and total scores improved significantly,with a statistically sign讦icant (Plt;0.05).Before treatment, the experimental