美索疗法子午流注运用于女性迟发性痤疮湿热蕴结型治疗的临床分析-临床医学专业毕业论文.docx

成都中医药大学硕士学位论文 成都中医药大学硕士学位论文 共 共 51 页 第 PAGE 1 页 中文摘要 目的 探讨美索疗法结合子午流注治疗 女性迟发性痤疮湿热 （瘀）蕴结型临床疗效及作用机理。 方法 将98例患者随机分成治疗组68例、对照组30例，治疗组用 美索疗法结合子午流注治疗，对照组用口服安体舒通( 螺内酯) 、美 满霉素、过氧苯甲酰乳膏三联疗法治疗。观察治疗组和对照组的临 床疗效，治疗前后血清T、E2、PRL、FSH、LH水平比较。 结果 治疗组和对照组总有效率分别为94. 12%、86. 67%，两组比 较差异无显著性（P0. 05）；治疗前治疗组及对照组血清T水平均高 于正常参考值（P0. 05）；治疗后治疗组血清T水平明显下降（P0. 05）, E2、PRL、FSH、LH水平变化不明显；对照组治疗后血清T、E2、PRL、 FSH、LH水平变化不明显（P0. 05）。 结论 美索疗法结合子午流注治疗女性迟发性痤疮湿热（瘀）蕴 结型临床疗效确切，可降低血清T水平，药物不良反应少。 关键词 迟发性痤疮 美索疗法 子午流注 湿热（瘀）蕴 结证 Abstract Obj ect i ve: To observe the clinical of the Mesot her apy- Mi dni ght moon ebb f l ow t her apy and study the mechanism for treatment of Dampness- Heat （st agnant ） syndr ome i n female post-adolescent acne. Met hods: Ninety-eight cases randomly divided into a treatment group (n=68) and a control group (n=30).The treatment group were treat by mesot her apy- Mi dni ght moon ebb f l ow t her apy, and the control group were treated by western medicine (including spironolactone, minocycline and benzoyl peroxide) respectively. Serum levels of testosterone(T)and estradiol(E2) ， follicle stimulating hormone (FSH),luteinizing hormone(LH), prolactin(PRL) in all patients as well as the clinical therapeutic effect of the treatments were observed and compared. Resul t s: The total effective rate in the treated group and the control group was94.12% and 86.67% respectively, comparison between them showed insignificant difference. Serum level of T in the patients before treatment were higher than that in healthy standards （P0.05）, And showed no difference between the treated group and the control group . After treatment, it lowered significantly in the treated group （P0.01）,but unchanged in the control group . E2、PRL、FSH、LH levels showed no significant change in both groups before and after treatment（P0.05）. Concl usi on：The mesot her apy- Mi dni ght moon ebb f l ow t her apy provides valid and reliable clinical effect in treating dampness- heat （st agnant ） syndr ome