12医院药物不良反应的监测跟处理资料.pptVIP

医院药品不良反应监测与处理 浙江大学医学院附属第二医院药剂科 江波 一、药品不良反应的定义 药品不良反应(Adverse Drug Reaction,ADR): 广义：指因用药引起的任何不良情况 WHO定义：A response to a drug which is noxious and unintended, and occurs at dose normally used in man for prophylaxis, diagnosis, or therapy of disease, or for the modification of physiological function. 我国：质量合格药品在正常用法用量情况下出现的与用药目的无关的或意外的有害反应。 ADR辨析 药物滥用（吸毒） 超量误用 伪劣药品 差错、事故(未按规定方法用药) 药品不良事件 (Adverse Drug Event, ADE) WHO定义：Any unwanted medical occurrence that may present during treatment with a phamaceutical product but which does not necessarily have a causal relationship with this threatment