凉山彝族农村居民高尿酸血症流行病学调查-内科学专业论文.docxVIP

西南医科大学硕士学位论文Prevalence 西南医科大学硕士学位论文 Prevalence of hyperuricemia among adult Yi rural residents in Liangshan region Abstract：0bjective：To investigate the levels of serum uric acid and prevalence rate of hyperuricemia(HUA)and other metabolic diseases among Yi rural residents in Liangshan Yi Automomous Prefecture(Liangshan)of Sichuan province；to explore predictive value of obesity and relevant metabolism indexes for hyperuricemia；SO to provide epidemiological evidences for dietary interventions and guidance for further prevention and control of HUA．Methods：Stratified random cluster sampling was adoped to select 972 permanent residents aged≥1 8 years in Liangshan for a cross—sectional study． Participants’demographic characteristics，health—related behaviors and dietary behaviors were obtained．Height，weight，blood pressure，waist circumference and hip circumference were measured．Venousblood samples were taken from each subj ects for measurements of blood biochemicalparameters included fasting plasma glucose(FPG)，blood fat(TC，TG，LDL—C，HDL—C)and the serum urid acid(SUA)．The collected data were analyzed by using SPSS 23．0(statistical package for social sciences)．Two—independent-samples f test were used for comparision of mean level of serum uric acid among different groups．Chi-square test was used for comparision of prevalence of HUA among different groups．Chi-square trend test was used for the trend analysis of prevalence of HUA．Single—variable and multi—variables logistic regression analysis were used toexplore risk factors of HUA．Spearman correlation was used to analyze the relationship between HUA and obesity indexes and receiver operating characteristic(ROC)curve was used to determine the best predictable value of HUA with maximum Gordon’S index as the best cut—off point．Results： (1)The prevalence rate of HUA in the population was 22．O％，3 0．4％inmen and 3 万方数据 西南医科大学硕士学位论文1 西南医科大学硕士学位论文 1 2．3％in women；there was a significant gender difference in HUA prevalence rate a