多烯磷脂酰胆碱在肝病临床应用的专家共识.pdf

( ) 2017 8 11 4 Chin J Exp Clin Infect Dis (Electronic Edition), August 2017, Vol.11, No.4 中华实验和临床感染病杂志电子版 年 月第 卷第 期 · 313 · · · 指南 多烯磷脂酰胆碱在肝病临床应用的专家共识 【摘要】 随着临床研究证据的积累，多烯磷脂酰胆碱已被我国多部肝病诊疗指南列为抗炎保肝 , 治疗药物。但限于篇幅，上述指南均未就多烯磷脂酰胆碱的具体临床应用展开论述 也未能给出详尽 的循证医学证据。为此，本文以多烯磷脂酰胆碱在各种肝病临床应用的结果作为证据，参照肝病诊疗 相关的各项指南和共识，结合肝病治疗的发展趋势，讨论并撰写本专家共识，以期为临床医生进一步 提供用药依据。 【关键词】 多烯磷脂酰胆碱；保肝；专家共识 Experts consensus on the treatment with polyenphosphatidylcholine in patients with liver diseases Committee of the treatment with polyenphosphatidylcholine in patients with liver diseases Abstract Polyenphosphatidylcholine are recommended to improve liver function in several national 【 】 guidelines based on the clinical evidence which showed that polyenphosphatidylcholine were effective in patients with multiple liver diseases. Due to the limited description of data on polyenphosphatidylcholine in previous guidelines, the comprehensive review of polyenphosphatidylcholine in patients with liver diseases is needed. The committee of the treatment with polyenphosphatidylcholine in patients with liver diseases published the present consensus to standardize the clinical use of polyenphosphatidylcholine in patients with liver diseases. Key words Polyenphosphatidylcholine; Liver protection; Consensus 【 】 一、概况 实践的不断深入以及文献的积累，专家委员会将对 多烯磷脂酰胆碱（polyenphosphatidylcholine ， 《共识》内容进行更新。 PPC PPC 二、多烯磷脂酰胆碱的作用机制 ）是保护肝细胞膜及抗炎保肝的药物。 在 治疗各类肝病中的应用现已积累了较多的循证医 PPC 由大豆中提取磷脂精制而成，其主要活性