第八章 解热镇痛药非甾体抗炎药.pptx

第八章　解热镇痛药、非甾体抗炎药antipyretic analgesics， nonsteroidal anti-inflammatory agents and Antigout DrugsLearning ObjectivesUpon completion of this chapter the student should be able to:1 Discuss the role of arachidonic acid (花生四烯酸), cyclooxygenase (COX) and prostaglandins（前列腺素） in mediating inflammation.2 Describe the anti-inflammatory and/or analgetic mechanism of action of:a. Salicylic acid （水杨酸） derivativesb. Arylanthranilic acids (fenamates) 灭酸类c. Arylalkanoic acids 芳基烷酸类d. Oxicams 昔康类e. COX-2 selective inhibitorsf. Acetaminophen 对乙酰氨基酚g. Disease-modifying antirheumatic drugs (DMARDs)3 Describe t